[ney-der, ney-deer]
Astronomy. the point on the celestial sphere directly beneath a given position or observer and diametrically opposite the zenith.
Astrology. the point of a horoscope opposite the midheaven: the cusp of the fourth house.
the lowest point; point of greatest adversity or despair.

1350–1400; Middle EnglishArabic naẓīr over against, opposite to (the zenith)

nadiral, adjective

nadir, zenith.

3. bottom, floor, foot, depths. Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2014.
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World English Dictionary
nadir (ˈneɪdɪə, ˈnæ-)
1.  the point on the celestial sphere directly below an observer and diametrically opposite the zenith
2.  the lowest or deepest point; depths: the nadir of despair
[C14: from Old French, from Arabic nazīr as-samt, literally: opposite the zenith]

Collins English Dictionary - Complete & Unabridged 10th Edition
2009 © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
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Word Origin & History

c.1391, in astronomical sense, from M.L. nadir, from Arabic nazir "opposite to," in nazir as-samt, lit. "opposite of the zenith," from nazir "opposite" + as-samt "zenith" (see zenith). Transf. sense of "lowest point (of anything)" is first recorded 1793.
Online Etymology Dictionary, © 2010 Douglas Harper
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American Heritage
Science Dictionary
nadir   (nā'dər)  Pronunciation Key 
The point on the celestial sphere that is directly below the observer (90 degrees below the celestial horizon). Compare zenith.
The American Heritage® Science Dictionary
Copyright © 2002. Published by Houghton Mifflin. All rights reserved.
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Example sentences
This spiritual nadir came as his career began to peak.
At the nadir, I was sleeping about 2-3 hours a night and writing or revising
  when everyone else was asleep.
We are close to the nadir of the human soul here.
And even at its nadir there were signs of awakening.
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