any of the thick-skinned, nonruminant ungulates, as the elephant, hippopotamus, and rhinoceros.
an elephant.
a person who is not sensitive to criticism, ridicule, etc.; a thick-skinned person.

1830–40; < Neo-Latin Pachyderma, assumed singular of Pachydermata (plural) obsolete order name < Greek pachý(s) thick + -dérmata, neuter plural of -dermatos -skinned, adj. derivative of dermat-, stem of dérma skin, derma1

pachydermal, pachydermous, pachydermic, pachydermoid, adjective Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2014.
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World English Dictionary
pachyderm (ˈpækɪˌdɜːm)
any very large thick-skinned mammal, such as an elephant, rhinoceros, or hippopotamus
[C19: from French pachyderme, from Greek pakhudermos thick-skinned, from pakhus thick + derma skin]

Collins English Dictionary - Complete & Unabridged 10th Edition
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Word Origin & History

1838, from Fr. pachyderme (c.1600), adopted as a biological term 1797 by Fr. naturalist Georges Léopole Chrétien Frédéric Dagobert, Baron Cuvier (1769-1832), from Gk. pachydermos "thick-skinned," from pachys "thick" (from PIE *bhengh-, cf. Skt. bahu- "much") + derma "skin."
Online Etymology Dictionary, © 2010 Douglas Harper
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American Heritage
Science Dictionary
pachyderm   (pāk'ĭ-dûrm')  Pronunciation Key 
Any of various large, thick-skinned mammals, such as the elephant, rhinoceros, or hippopotamus.
The American Heritage® Science Dictionary
Copyright © 2002. Published by Houghton Mifflin. All rights reserved.
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Example sentences
Some researchers are pointing to a species-wide trauma and the fraying of the fabric of pachyderm society.
What emerged was a portrait of pervasive pachyderm dysfunction.
So fans have begun camping out for hours to await the pachyderm procession.
The royal pachyderm is only one feature of this edition of the circus.
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