In the venereal disease the local trouble commences as a papule and breaks into an ulcer without having formed a pustule.
Involution is marked by cessation of oozing, subsidence of the papule and scar-like changes at the site of the lesion.
The disease pursues a regular course of papule, pustule, and sore; and is said never to recur.
This papule increases in superficial area, but not in height, and gradually loses its redness.
Slight exudation of plasma, with a few corpuscles, usually follows, and produces elevation of the papule itself.
papule pap·ule (pāp'yōōl)
n. pl. pap·ules or pap·u·lae (-yə-lē')
A small, solid, usually inflammatory elevation of the skin that does not contain pus.