a hole, or one of a series of holes, bored or punched through something, as those between individual postage stamps of a sheet to facilitate separation.
a hole made or passing through a thing.
the act of perforating.
the condition or state of being perforated.

1400–50; late Middle English < Medieval Latin perforātiōn- (stem of perforātiō) a boring through. See perforate, -ion Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2014.
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World English Dictionary
perforation (ˌpɜːfəˈreɪʃən)
1.  the act of perforating or the state of being perforated
2.  a hole or holes made in something
3.  a.  a method of making individual stamps, coupons, etc, easily separable by punching holes along their margins
 b.  perf the holes punched in this way

Collins English Dictionary - Complete & Unabridged 10th Edition
2009 © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009
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Word Origin & History

mid-15c., "action of perforating," from L.L. perforationem (nom. perforatio), from L. perforatus, pp. of perforare "bore or pierce through," from per- "through" + forare "to pierce" (see bore). Meaning "hole made through something" is recorded from 1540s.
Online Etymology Dictionary, © 2010 Douglas Harper
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American Heritage
Medical Dictionary

perforation per·fo·ra·tion (pûr'fə-rā'shən)

  1. The act of perforating or the state of being perforated.

  2. An abnormal opening in a hollow organ or viscus, as one made by rupture or injury.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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Example sentences
They had perforation, but they would do the trick anyway.
In the early centuries, the perforation of matzoth was an artistic job.
Bladder perforation is a rare and life-threatening event.
However, there's bound to be considerable perforation from tiny meteorites.
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