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pernicious anemia
noun
, Pathology.
- a severe anemia caused by the diminution or absence of stomach acid secretion, with consequent failure of the gastric mucosa to secrete the intrinsic factor necessary for the absorption of vitamin B 1 2 , characterized by a great reduction in the number of red blood cells and an increase in their size.
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Word History and Origins
Origin of pernicious anemia1
First recorded in 1870–75
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Example Sentences
It occurs in well-marked cases of pernicious anemia and leukemia, and, much less commonly, in very severe symptomatic anemias.
From Project Gutenberg
In pernicious anemia they are always greatly diminished, and an increase should exclude the diagnosis of this disease.
From Project Gutenberg
Megaloblasts are found in pernicious anemia, and with extreme rarity in any other condition.
From Project Gutenberg
Pathologically, normoblasts occur in severe symptomatic anemia, leukemia, and pernicious anemia.
From Project Gutenberg
A few of these may be present in very marked leukocytosis or any severe blood condition, as pernicious anemia.
From Project Gutenberg
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