pernicious

[per-nish-uhs]
adjective
1.
causing insidious harm or ruin; ruinous; injurious; hurtful: pernicious teachings; a pernicious lie.
2.
deadly; fatal: a pernicious disease.
3.
Obsolete. evil; wicked.

Origin:
1515–25; < Latin perniciōsus ruinous, equivalent to pernici(ēs) ruin (per- per- + -nici-, combining form of nex death, murder (stem nec-) + -iēs noun suffix) + -ōsus -ous

perniciously, adverb
perniciousness, noun
unpernicious, adjective
unperniciously, adverb


1. harmful, detrimental, deleterious, destructive, damaging, baneful, noxious, malicious. 2. lethal.
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Based on the Random House Dictionary, © Random House, Inc. 2014.
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Collins
World English Dictionary
pernicious (pəˈnɪʃəs)
 
adj
1.  wicked or malicious: pernicious lies
2.  causing grave harm; deadly
 
[C16: from Latin perniciōsus, from perniciēs ruin, from per- (intensive) + nex death]
 
per'niciously
 
adv
 
per'niciousness
 
n

Collins English Dictionary - Complete & Unabridged 10th Edition
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Etymonline
Word Origin & History

pernicious
1521, from M.Fr. pernicios (13c., Fr. pernicieux), from L. perniciosus "destructive," from pernicies "destruction, death, ruin," from per- "completely" + necis "violent death, murder," related to necare "to kill," nocere "to hurt, injure, harm," noxa "harm, injury" (see noxious).
Online Etymology Dictionary, © 2010 Douglas Harper
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American Heritage
Medical Dictionary

pernicious per·ni·cious (pər-nĭsh'əs)
adj.
Tending to cause death or serious injury; deadly.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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Example sentences
But a bias can be real, and pernicious, without being legally actionable.
But a more pernicious problem is the impact upon incentives of all firms.
In the end, he conveys the earnest message that pernicious substance abuse can
  be overcome with willpower and courage.
He resists any suggestion that his gambling addiction might be pernicious.
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