verb (used with object)
to cause to be puzzled or bewildered over what is not understood or certain; confuse mentally: Her strange response perplexed me.
to make complicated or confused, as a matter or question.
to hamper with complications, confusion, or uncertainty.

1585–95; back formation from perplexed

perplexer, noun
perplexingly, adverb
unperplexing, adjective

1. mystify, confound. 2. tangle, snarl. 3. vex, annoy, bother. Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2014.
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World English Dictionary
perplex (pəˈplɛks)
1.  to puzzle; bewilder; confuse
2.  to complicate: to perplex an issue
[C15: from obsolete perplex (adj) intricate, from Latin perplexus entangled, from per- (thoroughly) + plectere to entwine]

Collins English Dictionary - Complete & Unabridged 10th Edition
2009 © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009
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Example sentences
These are questions that perplex every student of Arabic.
After a slow opening that may perplex new readers, the action soon picks up.
I'll perplex him with my slow ball.
And at the top of the list of questions that perplex investors most is how to
  determine an investment's cost basis.
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