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[pree-di-spohz] /ˌpri dɪˈspoʊz/
verb (used with object), predisposed, predisposing.
to give an inclination or tendency to beforehand; make susceptible:
Genetic factors may predispose human beings to certain metabolic diseases.
to render subject, susceptible, or liable:
The evidence predisposes him to public censure.
to dispose beforehand.
Archaic. to dispose of beforehand, as in a will, legacy, or the like.
verb (used without object), predisposed, predisposing.
to give or furnish a tendency or inclination:
an underground job that predisposes to lung infection.
Origin of predispose
1640-50; pre- + dispose
Related forms
predisposal, noun
[pree-di-spoh-zid-lee, -spohzd-] /ˌpri dɪˈspoʊ zɪd li, -ˈspoʊzd-/ (Show IPA),
predisposedness, noun
unpredisposed, adjective
unpredisposing, adjective
1. prearrange, prepare. 3. bias, incline. Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2015.
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Examples from the web for predispose
  • Genes that predispose people to depression, though, also influence their risk of experiencing negative environmental events.
  • Certain genetic disorders predispose people to respiratory infections.
  • The results indicate that the cellular changes could predispose the prostate to disease in adulthood.
  • It should be a major goal of science to understand the genes that predispose us to do one thing as opposed to another.
  • Maybe getting cold and damp does not predispose people to catch a cold.
  • However, if your genes predispose you to asthma or obesity, eradication may be unwise.
  • Scientists know that small variations in certain genes can predispose people to cancers or heart disease.
  • We will live according to what our own specific genetic risks predispose us toward.
  • Antidepressants help with strokes, but surveys also show them to predispose to stroke.
  • We have already identified genes which predispose for many diseases.
British Dictionary definitions for predispose


verb (transitive)
often foll by to or towards. to incline or make (someone) susceptible to something beforehand
(mainly law) to dispose of (property, etc) beforehand; bequeath
Derived Forms
predisposal, noun
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition
© William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012
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Word Origin and History for predispose

1640s, "to put into a certain frame of mind," perhaps a back-formation from predisposition. Related: Predisposed; predisposing.

Online Etymology Dictionary, © 2010 Douglas Harper
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predispose in Medicine

predispose pre·dis·pose (prē'dĭ-spōz')
v. pre·dis·posed, pre·dis·pos·ing, pre·dis·pos·es
To make susceptible, as to a disease.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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