noun Genetics.
a patient who is the initial member of a family to come under study.
Also called propositus.

1925–30; < Latin probandus, gerundive of probāre to test, probe Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2014.
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World English Dictionary
proband (ˈprəʊbænd)
another name (esp US) for propositus
[C20: from Latin probandus, gerundive of probāre to test]

Collins English Dictionary - Complete & Unabridged 10th Edition
2009 © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009
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American Heritage
Medical Dictionary

proband pro·band (prō'bānd')
An individual or member of a family being studied in a genetic investigation. Also called index case, propositus.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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Example sentences
The brothers and sisters of the proband are called siblings.
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