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[sahy-koh-ak-tiv] /ˌsaɪ koʊˈæk tɪv/
of or pertaining to a substance having a profound or significant effect on mental processes:
a psychoactive drug.
1960-65; psycho- + active Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2014.
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Examples from the web for psychoactive
  • Tobacco is considered to be a mood and behavior altering substance that is psychoactive and abusable.
  • It's not really practical to go out in public while under the influence of psychoactive drugs.
  • Compared to alcohol, caffeine is on the other end of the spectrum of psychoactive drugs in that it is a stimulant.
  • Caffeine, a psychoactive drug used by nearly everybody, alters human neurochemistry.
  • Nowadays treatment by medical doctors nearly always means psychoactive drugs, that is, drugs that affect the mental state.
  • Some of the biggest blockbusters are psychoactive drugs.
  • Tobacco smoke may contain a psychoactive ingredient other than nicotine.
  • However, their acute psychoactive effects have been a problem.
British Dictionary definitions for psychoactive


capable of affecting mental activity: a psychoactive drug
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition
© William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012
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Word Origin and History for psychoactive

also psycho-active, 1959, from psycho- + active.

Online Etymology Dictionary, © 2010 Douglas Harper
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psychoactive in Medicine

psychoactive psy·cho·ac·tive (sī'kō-āk'tĭv)
Affecting the mind or mental processes. Used of a drug.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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