Do you know ghouls from goblins and ghosts?
1866, from Modern Latin, from Greek skleros "hard" (see sclerosis) + derma "skin" (see derma). Related: Sclerodermatous; sclerodermatic.
scleroderma scle·ro·der·ma (sklēr'ə-dûr'mə)n.
A pathological thickening and hardening of the skin caused by swelling and thickening of fibrous tissue. Also called dermatosclerosis.
See progressive systemic sclerosis.