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[skleer-uh-dur-muh, skler-] /ˌsklɪər əˈdɜr mə, ˌsklɛr-/
noun, Pathology
a disease in which connective tissue anywhere in the body becomes hardened and rigid.
Origin of scleroderma
1865-70; sclero- + -derma Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2015.
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British Dictionary definitions for scleroderma


a chronic progressive disease most common among women, characterized by a local or diffuse thickening and hardening of the skin
Word Origin
C19: from New Latin sclerōdermus, from Greek, from sklēros hard + derma skin
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition
© William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012
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Word Origin and History for scleroderma

1866, from Modern Latin, from Greek skleros "hard" (see sclerosis) + derma "skin" (see derma). Related: Sclerodermatous; sclerodermatic.

Online Etymology Dictionary, © 2010 Douglas Harper
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scleroderma in Medicine

scleroderma scle·ro·der·ma (sklēr'ə-dûr'mə)

  1. A pathological thickening and hardening of the skin caused by swelling and thickening of fibrous tissue. Also called dermatosclerosis.

  2. See progressive systemic sclerosis.

scle'ro·der'ma·tous (-mə-təs)
The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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scleroderma in Science
A connective tissue disease characterized by the deposition of fibrous tissue into the skin and often other organs, causing tissue hardening and thickening.
The American Heritage® Science Dictionary
Copyright © 2002. Published by Houghton Mifflin. All rights reserved.
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