setscrew

[set-skroo]
noun
a screw passing through a threaded hole in a part to tighten the contact of that part with another, as of a collar with the shaft on which it fits.

Origin:
1850–55; set + screw

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World English Dictionary
setscrew (ˈsɛtˌskruː)
 
n
a screw that fits into the boss or hub of a wheel, coupling, cam, etc, and prevents motion of the part relative to the shaft on which it is mounted

Collins English Dictionary - Complete & Unabridged 10th Edition
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Example sentences
The setscrew tightens the spring centering mechanism that keeps the loader in a neutral position.
Designed to retain mirror with concealed setscrew fastenings.
To improve the security of these windows, loosen the setscrew in the crank handle and remove the crank handle altogether.
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