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[sis] /sɪs/
noun, Informal.
Origin of sis
1825-35, Americanism; shortened form; compare Dutch zus for zuster sister


a suffix appearing in loanwords from Greek, where it was used to form from verbs abstract nouns of action, process, state, condition, etc.:
thesis; aphesis.
< Greek Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2015.
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Examples from the Web for sis
Contemporary Examples
Historical Examples
  • sis´yphos outwitted him by marking his sheep under their feet.

  • Beshrew me, sis, but since when didst thou shift to so fair a taste for—what was it?

    Historic Boys Elbridge Streeter Brooks
  • F they knowed what kind uh varmints I wuz arter over there, they wouldn't begrudge me nuthin', sis.

    The Graysons Edward Eggleston
  • sis, I made camp bread for twenty years afore you were born.

    The Forester's Daughter Hamlin Garland
  • He looked at her drolly, and added: "You played up to me fine, sis."

    A Texas Ranger William MacLeod Raine
  • No; I'll let you have it some day, sis, and you shall do what you like with it.

    Audrey Craven May Sinclair
  • sis and I had a couple of sets the other day, and she pretty nearly licked me.

    The Lucky Seventh Ralph Henry Barbour
  • Dear sis, You will be surprised to get a letter from me after all this time.

  • He crope 'roun', he did, but no diffunce which a-way he creep, dar wuz ole sis Cow hawns p'intin' right straight at 'im.

    Nights With Uncle Remus Joel Chandler Harris
British Dictionary definitions for sis


(informal) short for sister


/sɪs; siːs/
(South African, informal) an exclamation of disgust
Word Origin
Afrikaans, possibly from Khoi


Also called MI6. (in Britain) Secret Intelligence Service
(in New Zealand) Security Intelligence Service
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition
© William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012
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Word Origin and History for sis

1650s, abbreviated form of sister; in American English, applied generally to girls and young women (1859). It also was the familiar short form of Cecilie, Cicely, a common name for girls in the Middle English period.


suffix in Greek-derived nouns denoting action, process, state, condition, from Greek -sis, which is identical in meaning with Latin -entia, English -ing (1).

Online Etymology Dictionary, © 2010 Douglas Harper
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Slang definitions & phrases for sis



Risky; succeed-or-be-ruined: Playing cornerback in the National Football League, particularly for a young player, is a sink-or-swim proposition (1668+)

The Dictionary of American Slang, Fourth Edition by Barbara Ann Kipfer, PhD. and Robert L. Chapman, Ph.D.
Copyright (C) 2007 by HarperCollins Publishers.
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Related Abbreviations for sis


National Library of Medicine [Specialized Information Services]
The American Heritage® Abbreviations Dictionary, Third Edition
Copyright © 2005 by Houghton Mifflin Company.
Published by Houghton Mifflin Company. All rights reserved.
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