c.1600, of uncertain origin. The verb is attested from 1620s. A connection has been suggested to Middle French espraindre "to press out," from Latin exprimere, but the sense evolution is difficult.
An injury to a ligament when the joint is carried through a range of motion greater than its normal range without dislocation or fracture. v. sprained, sprain·ing, sprains
To cause a sprain to a joint or ligament.