[stahr-krawst, -krost]
thwarted or opposed by the stars; ill-fated: star-crossed lovers.

1585–95 Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2014.
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World English Dictionary
dogged by ill luck; destined to misfortune
[C16: from cross (in the sense: thwart): so called because of the astrological belief that the stars affect people's destinies]

Collins English Dictionary - Complete & Unabridged 10th Edition
2009 © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009
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Example sentences
But his relationship with the magazine was star-crossed at virtually every turn.
It's that star-crossed time when our species seem to collectively reach out for salvation.
But that tale of star-crossed teenage lovers may seem to leave out all those boys pining for their bunkmate across the barracks.
In three tumultuous decades as a professional golfer, he has been a star and star-crossed.
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