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1540s, from Latin suppurationem (nominative suppuratio), noun of action from past participle stem of suppurare "form or discharge pus," from sub "under" (see sub-) + stem of pus (see pus).
suppuration sup·pu·ra·tion (sŭp'yə-rā'shən)n. The formation or discharge of pus. Also called pyesis, pyopoiesis, pyosis.