noun Informal.
an act or instance of dissent, disapproval, etc.

1885–90 Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2014.
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Example sentences
It even gave users a chance to click thumbs-up or thumbs-down buttons on ads.
Rather than using a simple thumbs-up or thumbs-down, users can rate people at
  six levels of trustworthiness.
If you aren't digging a song suggestion, give it a thumbs-down.
The consultant, however, gave an emphatic thumbs-down.
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