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variable region

noun

, Immunology.
  1. a configuration in the upper branches of the Y of an antibody molecule, unique in each antibody type, that binds with the determinant of a specific antigen.


variable region

  1. The portion of the amino (NH 2 ) terminal of an antibody's heavy and light chains having a variable amino acid sequence. The structure of the variable region determines the antigenic specificity of the antibody.


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