It rises above all vicissitude, and enjoys sweet converse with the unchangeable and eternal Source of all real good.
Every grief hath that opportunity of cure; every joy that peril of vicissitude.
Such was the man to whom, after a short eventful period of peril and vicissitude, it was the lot of Flora Macdonald to be united.
The Sun shone on it: the vicissitude of seasons and human fortunes.
But it is not good to look too long upon these turning wheels of vicissitude, lest we become giddy.
What dark treasure-houses of vicissitude and woe are our memories become!
Time and vicissitude had effaced the wounds, and the Light of the Beautiful dawned once more in the face of Evelyn.
When a child, I was abandoned to every vicissitude—and I am lost.
But, on the whole, death and vicissitude had done very little.
So great a vicissitude in his life could not at once be received as real.
1560s, from Middle French vicissitude (14c.), from Latin vicissitudinem (nominative vicissitudo) "change," from vicissim "changeably, in turn," from vicis "a turn, change" (see vicarious). Related: Vicissitudes.