Art must be used in service of the people—and is always subject to the vicissitudes of the party line.
One by one, nine men, all military veterans, updated the judge on the vicissitudes of their week.
But no matter what the vicissitudes of life, I am still glad that I came of age in Boston, and that it taught me what it did.
1560s, from Middle French vicissitude (14c.), from Latin vicissitudinem (nominative vicissitudo) "change," from vicissim "changeably, in turn," from vicis "a turn, change" (see vicarious). Related: Vicissitudes.