[vir-yuh-luhnt, vir-uh-]
actively poisonous; intensely noxious: a virulent insect bite.
Medicine/Medical. highly infective; malignant or deadly.
Bacteriology. causing clinical symptoms.
violently or spitefully hostile.
intensely bitter, spiteful, or malicious: a virulent attack.

1350–1400; Middle English verulent < Latin vīrulentus, equivalent to vīr(us) poison (see virus) + -ulentus -ulent

virulently, adverb
hypervirulent, adjective
hypervirulently, adverb
nonvirulent, adjective
nonvirulently, adverb
supervirulent, adjective
supervirulently, adverb
unvirulent, adjective
unvirulently, adverb

violent, virulent.

1. venomous. 5. vicious, acerbic.

1. harmless. Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2014.
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World English Dictionary
virulent (ˈvɪrʊlənt)
1.  a.  (of a microorganism) extremely infective
 b.  (of a disease) having a rapid course and violent effect
2.  extremely poisonous, injurious, etc
3.  extremely bitter, hostile, etc
[C14: from Latin vīrulentus full of poison, from vīrus poison; see virus]

Collins English Dictionary - Complete & Unabridged 10th Edition
2009 © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009
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Word Origin & History

1400, in ref. to wounds, ulcers, etc., "full of corrupt or poisonous matter," from L. virulentus "poisonous," from virus "poison" (see virus). Fig. sense of "violent, spiteful" is attested from 1607.
Online Etymology Dictionary, © 2010 Douglas Harper
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American Heritage
Medical Dictionary

virulent vir·u·lent (vēr'yə-lənt, vēr'ə-)

  1. Extremely infectious, malignant, or poisonous. Used of a disease or toxin.

  2. Capable of causing disease by breaking down protective mechanisms of the host. Used of a pathogen.

  3. Intensely irritating, obnoxious, or harsh.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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Example sentences
The typical safety office will monitor biohazards produced from research on,
  say, a virulent virus or bacterium.
On good days, her virulent negativity was channeled into wit.
The act would not have been a beauty-spot upon the cheek of his reputation to
  embellish it, but a virulent ulcer disfiguring it.
It turns out that low-gravity conditions can do strange things to earthling
  cells, including making them more virulent.
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