a particular occupation, business, or profession; calling.
a strong impulse or inclination to follow a particular activity or career.
a divine call to God's service or to the Christian life.
a function or station in life to which one is called by God: the religious vocation; the vocation of marriage.

1400–50; late Middle English vocacio(u)n < Latin vocātiōn- (stem of vocātiō) a call, summons, equivalent to vocāt(us) past participle of vocāre to call (see -ate1) + -iōn- -ion

1. avocation, vocation ; 2. vacation, vocation.

1. employment, pursuit.
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Based on the Random House Dictionary, © Random House, Inc. 2014.
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World English Dictionary
vocation (vəʊˈkeɪʃən)
1.  a specified occupation, profession, or trade
2.  a.  a special urge, inclination, or predisposition to a particular calling or career, esp a religious one
 b.  such a calling or career
[C15: from Latin vocātiō a calling, from vocāre to call]

Collins English Dictionary - Complete & Unabridged 10th Edition
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Word Origin & History

early 15c., "spiritual calling," from L. vocationem (nom. vocatio), lit. "a calling," from vocatus "called," pp. of vocare "to call" (see voice). Sense of "one's occupation or profession" is first attested 1550s.
Online Etymology Dictionary, © 2010 Douglas Harper
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Example sentences
Although he could not have known it at the time, he had found his life's
But his vocation is computers, and he has always been fascinated with
They'll be serious scientists seriously out of a vocation.
He thus belonged to the gentry, and it seems likely that he entered the church
  more as a profession than a vocation.
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