having extensive knowledge, as in one particular subject or in a variety of subjects.

1400–50; late Middle English

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Cite This Source Link To well-informed
World English Dictionary
1.  having knowledge about a great variety of subjects: he seems to be a well-informed person
2.  possessing reliable information on a particular subject

Collins English Dictionary - Complete & Unabridged 10th Edition
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Example sentences
Here's a well-reasoned explanation as to why one reasonably smart and
  well-informed family won't be getting flu shots this year.
By contrast, well-informed people are more likely to ask others for help.
But, in regard to the other point, there is no possibility of rational and
  well-informed doubt.
Extremely well-informed people also get in touch to insist that there is really
  only one doctor, or only one clinic.
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