verb (used with object), antagonized, antagonizing.
to make hostile or unfriendly; make an enemy or antagonist of: His speech antagonized many voters.
to act in opposition to; oppose.
verb (used without object), antagonized, antagonizing.
Rare. to act antagonistically.
Also, especially British, antagonise.

1625–35; < Greek antagōnízesthai to contend against, dispute with. See ant-, agonize

antagonizable, adjective
antagonization, noun
reantagonize, verb (used with object), reantagonized, reantagonizing.
unantagonizable, adjective
unantagonized, adjective
unantagonizing, adjective
unantagonizingly, adverb Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2014.
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World English Dictionary
antagonize or antagonise (ænˈtæɡəˌnaɪz)
1.  to make hostile; annoy or irritate
2.  to act in opposition to or counteract
[C17: from Greek antagōnizesthai, from anti- + agōnizesthai to strive, from agōn contest]
antagonise or antagonise
[C17: from Greek antagōnizesthai, from anti- + agōnizesthai to strive, from agōn contest]
an'tagonizable or antagonise
an'tagonisable or antagonise
antagoni'zation or antagonise
antagoni'sation or antagonise

Collins English Dictionary - Complete & Unabridged 10th Edition
2009 © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009
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Word Origin & History

1630s, "to compete with," from Gk. antagonizesthai "to struggle against" (see antagonist). Meaning "to struggle against continuously" is recorded from 1742.
Online Etymology Dictionary, © 2010 Douglas Harper
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Example sentences
It is how he interprets their behavior and motives that has both enthralled and antagonized his critics.
But he antagonized the city by delaying tax payments, causing city workers to go unpaid for months.
The slogans antagonized his customers and often got him into ideological hot water.
But cost control antagonized both physicians and patients.
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