| 1. | a person who is opposed to, struggles against, or competes with another; opponent; adversary. |
| 2. | the adversary of the hero or protagonist of a drama or other literary work: Iago is the antagonist of Othello. |
| 3. | Physiology. a muscle that acts in opposition to another. Compare agonist (def. 3). |
| 4. | Dentistry. a tooth in one jaw that articulates during mastication or occlusion with a tooth in the opposing jaw. |
| 5. | Pharmacology. a drug that counteracts the effects of another drug. |
antagonist an·tag·o·nist (ān-tāg'ə-nĭst)
n.
Something, such as a muscle, disease, or physiological process, that neutralizes or impedes the action or effect of another.