noun, verb, plagued, pla⋅guing.| 1. | an epidemic disease that causes high mortality; pestilence. |
| 2. | an infectious, epidemic disease caused by a bacterium, Yersinia pestis, characterized by fever, chills, and prostration, transmitted to humans from rats by means of the bites of fleas. Compare bubonic plague, pneumonic plague, septicemic plague. |
| 3. | any widespread affliction, calamity, or evil, esp. one regarded as a direct punishment by God: a plague of war and desolation. |
| 4. | any cause of trouble, annoyance, or vexation: Uninvited guests are a plague. |
| 5. | to trouble, annoy, or torment in any manner: The question of his future plagues him with doubt. |
| 6. | to annoy, bother, or pester: Ants plagued the picnickers. |
| 7. | to smite with a plague, pestilence, death, etc.; scourge: those whom the gods had plagued. |
| 8. | to infect with a plague; cause an epidemic in or among: diseases that still plague the natives of Ethiopia. |
| 9. | to afflict with any evil: He was plagued by allergies all his life. |

plague (plāg) n.
[Middle English plage, blow, calamity, plague, from Late Latin plāga, from Latin, blow, wound; see plāk-2 in Indo-European roots. V., Middle English plaghen, from Middle Dutch, from plaghe, plague, from Late Latin plāga.] plagu'er n. |
A highly contagious disease, such as bubonic plague, that spreads quickly throughout a population and causes widespread sickness and death.
Note: The term is also used to refer to widespread outbreaks of many kinds, such as a “plague of locusts.”
plague (plāg)
n.
A highly infectious, usually fatal, epidemic disease, especially bubonic plague.