to distress with mental or bodily pain; trouble greatly or grievously: to be afflicted with arthritis.
2.
Obsolete.
a.
to overthrow; defeat.
b.
to humble.
Origin: 1350–1400; Middle English afflicten < Latin afflīctus distressed, past participle of afflīgere to cast down (af-af- + flīg- knock + -tus past participle suffix); replacing Middle English aflight < Middle French aflit < L. See inflict