ag·o·nize

[ag-uh-nahyz] verb, ag·o·nized, ag·o·niz·ing.
verb (used without object)
1.
to suffer extreme pain or anguish; be in agony.
2.
to put forth great effort of any kind.
verb (used with object)
3.
to distress with extreme pain; torture.
Also, especially British, ag·o·nise.


Origin:
1575–85; < Medieval Latin agōnizāre < Greek agōnízesthai to struggle (for a prize), equivalent to agōn- agon + -izesthai -ize

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Based on the Random House Dictionary, © Random House, Inc. 2013.
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World English Dictionary
agonize or agonise (ˈæɡəˌnaɪz) [Click for IPA pronunciation guide]
 
vb
1.  to suffer or cause to suffer agony
2.  (intr) to make a desperate effort; struggle; strive
 
[C16: via Medieval Latin from Greek agōnizesthai to contend for a prize, from agōnagon]
 
agonise or agonise
 
vb
 
[C16: via Medieval Latin from Greek agōnizesthai to contend for a prize, from agōnagon]
 
'agonizingly or agonise
 
adv
 
'agonisingly or agonise
 
adv

Collins English Dictionary - Complete & Unabridged 10th Edition
2009 © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009
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Etymonline
Word Origin & History

agonize
1580s, "to torture," from M.L. agonizare, from Gk. agonizesthai "to contend in the struggle" (see agony). Intrans. sense of "to suffer physical pain" is recorded from 1660s. That of "to worry intensely" is from 1853.
Online Etymology Dictionary, © 2010 Douglas Harper
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Example sentences
Society sees the few people making a spectacle, not the many who agonize in
  secret.
But she soon realizes that she is not at all sure about what she wants to do,
  and she continues to agonize over her decision.
Philosophers agonize about whether the reality outside that circle even exists.
It's downright destructive to agonize over your body's imperfections.
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