agonize

[ag-uh-nahyz]
verb (used without object), agonized, agonizing.
1.
to suffer extreme pain or anguish; be in agony.
2.
to put forth great effort of any kind.
verb (used with object), agonized, agonizing.
3.
to distress with extreme pain; torture.
Also, especially British, agonise.


Origin:
1575–85; < Medieval Latin agōnizāre < Greek agōnízesthai to struggle (for a prize), equivalent to agōn- agon + -izesthai -ize

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World English Dictionary
agonize or agonise (ˈæɡəˌnaɪz)
 
vb
1.  to suffer or cause to suffer agony
2.  (intr) to make a desperate effort; struggle; strive
 
[C16: via Medieval Latin from Greek agōnizesthai to contend for a prize, from agōnagon]
 
agonise or agonise
 
vb
 
[C16: via Medieval Latin from Greek agōnizesthai to contend for a prize, from agōnagon]
 
'agonizingly or agonise
 
adv
 
'agonisingly or agonise
 
adv

Collins English Dictionary - Complete & Unabridged 10th Edition
2009 © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009
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Etymonline
Word Origin & History

agonize
1580s, "to torture," from M.L. agonizare, from Gk. agonizesthai "to contend in the struggle" (see agony). Intrans. sense of "to suffer physical pain" is recorded from 1660s. That of "to worry intensely" is from 1853.
Online Etymology Dictionary, © 2010 Douglas Harper
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Example sentences
Still, despite peer-reviewed evidence, many parents ignore the math and agonize
  about whether to vaccinate.
Philosophers agonize about whether the reality outside that circle even exists.
They themselves agonize over the restraints they face.
The ice cream and topping are so good that you don't even need to agonize over
  the short cake.
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