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[al-uh-pyoo r-uh-nawl, -nol] /ˌæl əˈpyʊər əˌnɔl, -ˌnɒl/
noun, Pharmacology
a substance, C 5 H 4 N 4 O, used primarily in the treatment of chronic gout to decrease the synthesis of uric acid.
1960-65; apparently allo- + purine + -ol1 Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2015.
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Examples from the web for allopurinol
  • allopurinol is a xanthine oxidase inhibitor that blocks uric acid production.
  • Daily use of allopurinol or probenecid decrease uric acid levels in your blood.
  • Such treatments might include sodium bicarbonate, allopurinol, and aluminum hydroxide or calcium carbonate.
British Dictionary definitions for allopurinol


a synthetic drug that reduces blood concentrations of uric acid and is administered orally in the treatment of gout. Formula: C5H4N4O
Word Origin
C20: from allo- + purine + -ol1
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition
© William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012
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allopurinol in Medicine

allopurinol al·lo·pu·ri·nol (āl'ō-pyur'ə-nôl', -nōl')
A drug that inhibits the synthesis of uric acid and is used to treat gout and other hyperuricemic conditions.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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Encyclopedia Article for allopurinol

drug used in the treatment of gout, a disease that is characterized by severe inflammation in one or more of the joints of the extremities. Allopurinol inhibits an enzyme that is necessary to form uric acid, a substance present in abnormally large amounts in the blood of persons with gout that forms solid deposits in the joints, the kidneys, and other tissues. The drug reduces the amount of uric acid produced by the body and fosters the resorption of solid deposits in the joints, thus improving joint function

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Encyclopedia Britannica, 2008. Encyclopedia Britannica Online.
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