[uh-muhk, uh-mok]
(among members of certain Southeast Asian cultures) a psychic disturbance characterized by depression followed by a manic urge to murder.
run/go amok. amuck ( def 3 ).
Also, amuck.

1865–70; < Malay amuk Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2014.
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World English Dictionary
amok or amuck (əˈmʌk, əˈmɒk, əˈmʌk)
1.  a state of murderous frenzy, originally observed among Malays
2.  run amok to run about with or as if with a frenzied desire to kill
[C17: from Malay amoq furious assault]
amuck or amuck
[C17: from Malay amoq furious assault]

Collins English Dictionary - Complete & Unabridged 10th Edition
2009 © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009
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Word Origin & History

in phrase to run amok first recorded 1670s, from Malay amuk "attacking furiously." Earlier the word was used as a noun or adj. meaning "a frenzied Malay," originally in the Port. form amouco or amuco.
"There are some of them [the Javanese] who ... go out into the streets, and kill as many persons as they meet. ... These are called Amuco." ["The Book of Duarte Barbosa: An Account of the Countries Bordering on the Indian Ocean and Their Inhabitants," c.1516, Eng. transl.]
Cf. amuck.
Online Etymology Dictionary, © 2010 Douglas Harper
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Example sentences
But more is needed to understand and significantly treat self-destructive
  behavior run amok.
There sure is a lot of ignorance running amok on these days.
My expectations have been raised to this ridiculous level by technology running
  amok through my heretofore-bucolic existence.
Changing the text of the author seems to me to be the height of arrogance and
  as others have said, an example of pc run amok.
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