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[an-tee-di-pres-uh nt, an-tahy-] /ˌæn ti dɪˈprɛs ənt, ˌæn taɪ-/ Pharmacology
of or relating to a substance that is used in the treatment of mood disorders, as characterized by various manic or depressive affects.
Also called energizer, psychic energizer. any such substance, as a tricyclic antidepressant, MAO inhibitor, or lithium.
Also, anti-depressant, antidepressive [an-tee-di-pres-iv, an-tahy-] /ˌæn ti dɪˈprɛs ɪv, ˌæn taɪ-/ (Show IPA).
Origin of antidepressant
1960-65; anti- + depressant Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2015.
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Examples from the web for antidepressant
  • My husband has been able to get off his antidepressant medication with the blessings of his doctor.
  • The use of antidepressant drugs are becoming equally common.
  • No wonder one of our break room topics is who is taking which antidepressant.
  • In other words, the brain's anticonvulsant mechanism may alter the brain's neurochemistry, acting as a built-in antidepressant.
  • The company is also developing a blood test to monitor antidepressant therapy.
  • Doctors are writing a new prescription for menopause: the antidepressant.
  • If depression recurs, then the patient should go back on the antidepressant.
  • Amitriptyline hydrochloride is a type of prescription medicine called a tricyclic antidepressant.
  • antidepressant link to cancer absent in industry studies.
  • Such side effects were also more likely to be serious among the antidepressant recipients than among the placebo group.
British Dictionary definitions for antidepressant


any of a class of drugs used to alleviate depression
of or relating to this class of drugs
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition
© William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012
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Word Origin and History for antidepressant

1876, from anti- + depressant.

Online Etymology Dictionary, © 2010 Douglas Harper
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antidepressant in Medicine

antidepressant an·ti·de·pres·sant (ān'tē-dĭ-prěs'ənt, ān'tī-)
A drug used to prevent or relieve mental depression.

an'ti·de·pres'sive (-prěs'ĭv) adj.
The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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antidepressant in Science
  (ān'tē-dĭ-prěs'ənt, ān'tī-)   
A drug used to prevent or treat depression.
The American Heritage® Science Dictionary
Copyright © 2002. Published by Houghton Mifflin. All rights reserved.
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