a presumed region in the human brain, possibly the hypothalamus, that functions to adjust appetite.

appe(tite) + -stat Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2014.
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World English Dictionary
appestat (ˈæpɪstæt)
a neural control centre within the hypothalamus of the brain that regulates the sense of hunger and satiety
[C20: from appe(tite) + -stat]

Collins English Dictionary - Complete & Unabridged 10th Edition
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American Heritage
Medical Dictionary

appestat ap·pe·stat (āp'ĭ-stāt')
The area in the brain that is believed to regulate appetite and food intake.

The American Heritage® Stedman's Medical Dictionary
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