noun Pathology.
the initial lesion of syphilis and certain other infectious diseases, commonly a more or less distinct ulcer or sore with a hard base.

1595–1605; < Middle FrenchLatin cancrum, accusative of cancer cancer

chancrous, adjective Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2014.
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World English Dictionary
chancre (ˈʃæŋkə)
pathol a small hard nodular growth, which is the first diagnostic sign of acquired syphilis
[C16: from French, from Latin: cancer]

Collins English Dictionary - Complete & Unabridged 10th Edition
2009 © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
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Word Origin & History

c.1605, "venereal ulcer," from Fr. chancre, lit. "cancer," from L. cancer (see cancer).
Online Etymology Dictionary, © 2010 Douglas Harper
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American Heritage
Medical Dictionary

chancre chan·cre (shāng'kər)
The primary lesion of syphilis; a hard, nonsensitive, dull red papule or area of infiltration that begins at the site of infection after an interval of 10 to 30 days. Also called hard chancre, hard ulcer.

chan'crous (-krəs) adj.
The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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Example sentences
He browbeats his doctor into imagining how the composer must have felt when he discovered a syphilitic chancre.
The chancre is generally painless and resolves without treatment.
The characteristic lesion of primary syphilis is the chancre, but atypical primary lesions may occur.
The rash usually does not itch and can appear as the chancre is healing or several weeks after the chancre has gone away.
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