de·pop·u·late (dē-pŏp'yə-lāt') tr.v.
de·pop·u·lat·ed, de·pop·u·lat·ing, de·pop·u·lates To reduce sharply the population of, as by disease, war, or forcible relocation.
[Latin dēpopulāri, dēpopulāt-, to lay waste : dē-, de- + populārī, to ravage (from populus, people, throng).] de·pop'u·la'tion n., de·pop'u·la'tor n.