discombobulate

[dis-kuhm-bob-yuh-leyt]
verb (used with object), discombobulated, discombobulating.
to confuse or disconcert; upset; frustrate: The speaker was completely discombobulated by the hecklers.

Origin:
1825–35, Americanism; fanciful alteration of discompose or discomfort

discombobulation, noun
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World English Dictionary
discombobulate (ˌdɪskəmˈbɒbjʊˌleɪt)
 
vb
informal chiefly (US), (Canadian) (tr) to throw into confusion
 
[C20: probably a whimsical alteration of discompose or discomfit]

Collins English Dictionary - Complete & Unabridged 10th Edition
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Etymonline
Word Origin & History

discombobulate
1834, Amer.Eng., fanciful coinage of a type popular then (originally discombobricate). Related: discombobulating; discombobulation.
Online Etymology Dictionary, © 2010 Douglas Harper
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Example sentences
It goes through a constant process of discombobulation as entrepreneurs invent new products and processes.
So there will be some discombobulation in that process.
Three years of discombobulation and aching need finally ended at midnight yesterday.
Anger may fuel her diatribes, but it is astutely balanced by the frank discombobulation that makes her one of us.
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