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enchiridion

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en⋅chi⋅rid⋅i⋅on

[en-kahy-rid-ee-uhn, -ki-]
–noun, plural -rid⋅i⋅ons, -rid⋅i⋅a [-rid-ee-uh] .
a handbook; manual.

Origin:
1535–45; < LL < Gk encheirídion handbook, equiv. to en- en- 2 + cheír hand + -idion dim. suffix
Dictionary.com Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2009.
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en·chi·rid·i·on   (ěn'kī-rĭd'ē-ən)   
n.   pl. en·chi·rid·i·ons or en·chi·rid·i·a (-ē-ə)
A handbook; a manual.

[Late Latin enchīridion, from Greek enkheiridion : en-, in; see en-2 + kheir, hand; see ghes- in Indo-European roots + -idion, diminutive suff.]
The American Heritage® Dictionary of the English Language, Fourth Edition
Copyright © 2009 by Houghton Mifflin Company.
Published by Houghton Mifflin Company. All rights reserved.
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Word Origin & History

enchiridion 
1541, "a handbook," from L.L., from Gk. enkheiridion, neut. of enkheiridios "that which is held in the hand," from en- "in" + kheir "hand."
Online Etymology Dictionary, © 2001 Douglas Harper
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