[es-truh-dahy-awl, -ol]
Biochemistry. an estrogenic hormone, C 18 H 24 O 2 , produced by the maturing Graafian follicle, that causes proliferation and thickening of the tissues and blood vessels of the endometrium.
Pharmacology. a commercial form of this compound, obtained from the urine of pregnant humans and mares or synthesized, used in the treatment of estrogen deficiency and certain menopausal and postmenopausal conditions.

1930–35; estra- (combining form representing estrin) + di-1 + -ol1 Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2014.
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World English Dictionary
estradiol (ˌɛstrəˈdaɪɒl, ˌiːstrə-)
the US spelling of oestradiol

oestradiol or (US) estradiol (ˌiːstrəˈdaɪɒl, ˌɛstrə-)
the most potent oestrogenic hormone secreted by the mammalian ovary: synthesized and used to treat oestrogen deficiency and cancer of the breast. Formula: C18H24O2
[C20: from New Latin, from oestrin + di-1 + -ol1]
estradiol or (US) estradiol
[C20: from New Latin, from oestrin + di-1 + -ol1]

Collins English Dictionary - Complete & Unabridged 10th Edition
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American Heritage
Medical Dictionary

estradiol es·tra·di·ol (ěs'trə-dī'ôl', -ōl')
The most potent naturally occurring estrogen.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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Example sentences
Estradiol is the hormone that increases through the first half of the cycle and peaks at ovulation.
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