histamine

[his-tuh-meen, -min]
noun
1.
Biochemistry, Physiology. a heterocyclic amine, C 5 H 9 N 3 , released by mast cells when tissue is injured or in allergic and inflammatory reactions, causing dilation of small blood vessels and smooth muscle contraction.
2.
Pharmacology. a commercial form of this compound, obtained from histidine and used chiefly in the diagnosis of gastric and circulatory functions.
Also, histamin [his-tuh-min] .
Compare antihistamine.


Origin:
1910–15; hist(idine) + -amine

histaminic [his-tuh-min-ik] , adjective
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World English Dictionary
histamine (ˈhɪstəˌmiːn, -mɪn)
 
n
See also antihistamine an amine formed from histidine and released by the body tissues in allergic reactions, causing irritation. It also stimulates gastric secretions, dilates blood vessels, and contracts smooth muscle. Formula: C5H9N3
 
[C20: from hist(idine) + -amine]
 
histaminic
 
adj

Collins English Dictionary - Complete & Unabridged 10th Edition
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American Heritage
Medical Dictionary

histamine his·ta·mine (hĭs'tə-mēn', -mĭn)
n.
A physiologically active depressor amine found in plant and animal tissue, derived from histidine by decarboxylation and released from cells in the immune system as part of an allergic reaction. It is a powerful stimulant of gastric secretion, constrictor of bronchial smooth muscle, and vasodilator.


his'ta·min'ic (-mĭn'ĭk) adj.
The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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American Heritage
Science Dictionary
histamine   (hĭs'tə-mēn')  Pronunciation Key 
An organic compound found widely in animals and plants that in humans and other mammals is released as part of the body's immune response, causing physiological changes including dilation of the blood vessels, contraction of smooth muscle (as in the airways), and increased gastric acid secretion. The itching and sneezing typical of respiratory allergies are caused by the release of histamine. Chemical formula: C5H9N3
The American Heritage® Science Dictionary
Copyright © 2002. Published by Houghton Mifflin. All rights reserved.
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Example sentences
Those travel to cells that release histamine and other chemicals and cause an
  allergic reaction.
The researchers detected a spike in the calcium levels inside the cells, which
  is the first step in histamine secretion.
During the reaction, histamine and other chemicals are released into the
  bloodstream.
Histamine is one of the chemicals released when antibodies overreact to
  allergens.
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