| 1. | Physiology. a histidine-derived amine compound that is released mainly by damaged mast cells in allergic reactions, causing dilation and permeability of blood vessels and lowering blood pressure. |
| 2. | Pharmacology. a commercial form of this compound, obtained from histidine and used chiefly in the diagnosis of gastric and circulatory functions. |
histamine his·ta·mine (hĭs'tə-mēn', -mĭn)
n.
A physiologically active depressor amine found in plant and animal tissue, derived from histidine by decarboxylation and released from cells in the immune system as part of an allergic reaction. It is a powerful stimulant of gastric secretion, constrictor of bronchial smooth muscle, and vasodilator.