[ahy-suh-ley-shuhn, is-uh-]
an act or instance of isolating.
the state of being isolated.
the complete separation from others of a person suffering from contagious or infectious disease; quarantine.
the separation of a nation from other nations by isolationism.
Psychoanalysis. a process whereby an idea or memory is divested of its emotional component.
Sociology, social isolation.

1825–35; isolate + -ion

anti-isolation, adjective
postisolation, adjective
reisolation, noun

2. See solitude. 3. segregation. Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2014.
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World English Dictionary
isolation (ˌaɪsəˈleɪʃən)
1.  the act of isolating or the condition of being isolated
2.  (of a country, party, etc) nonparticipation in or withdrawal from international politics
3.  med
 a.  Compare quarantine social separation of a person who has or is suspected of having a contagious disease
 b.  (as modifier): an isolation hospital
4.  sociol a lack of contact between persons, groups, or whole societies
5.  social psychol the failure of an individual to maintain contact with others or genuine communication where interaction with others persists
6.  in isolation without regard to context, similar matters, etc

Collins English Dictionary - Complete & Unabridged 10th Edition
2009 © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
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Word Origin & History

1833, from Fr. isolation, noun of action from isoler (see isolated).
Online Etymology Dictionary, © 2010 Douglas Harper
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American Heritage
Medical Dictionary

isolation i·so·la·tion (ī'sə-lā'shən)
The act of isolating or the state of being isolated.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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Encyclopedia Britannica


in medicine, separation of an infected individual (human or animal) from the healthy until that individual is no longer able to transmit the disease. In its strictest sense, the practice of isolation differs from that of quarantine, which is the detention of an individual who may have been exposed to a communicable disease until it is deemed certain that he has escaped infection. See quarantine

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Encyclopedia Britannica, 2008. Encyclopedia Britannica Online.
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Example sentences
His late years would be less tumultuous, but at a price of personal isolation.
He sometimes defended his isolation as necessary to produce his work.
He lives there in almost total isolation, as the owners don't know how to care
  for an ape.
We can never again stand aside, prideful in isolation.
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