[ma-leyz, -muh-; French ma-lez]
a condition of general bodily weakness or discomfort, often marking the onset of a disease.
a vague or unfocused feeling of mental uneasiness, lethargy, or discomfort.

1760–70; < French, Old French; see mal-, ease Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2014.
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World English Dictionary
malaise (mæˈleɪz)
1.  a feeling of unease or depression
2.  a mild sickness, not symptomatic of any disease or ailment
3.  a complex of problems affecting a country, economy, etc: Bulgaria's economic malaise
[C18: from Old French, from mal bad + aiseease]

Collins English Dictionary - Complete & Unabridged 10th Edition
2009 © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
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Word Origin & History

1768, from Fr. malaise, lit. "ill-ease," from mal "bad" + aise "ease" (see ease).
Online Etymology Dictionary, © 2010 Douglas Harper
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American Heritage
Medical Dictionary

malaise mal·aise (mā-lāz', -lěz')
A vague feeling of bodily discomfort, as at the beginning of an illness.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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Example sentences
Troubled by what he saw as China's spiritual malaise, he soon abandoned
  medicine to pursue literature.
This creates a sort of malaise because they'll never be satisfied.
And he comes to grip with a malaise that has been with him since childhood.
There's ample melody in the music, and the lyrics hold anguish and malaise.
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