the soft, deep-gray, fragile fur of the mole.
a strong and heavy napped, twilled cotton fabric used for sportswear and work clothing.
moleskins, a garment, especially trousers, of this fabric.
a soft, usually adhesive-backed fabric applied to the feet or other areas of the body to prevent irritation or abrasion.

1660–70; mole1 + skin Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2014.
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World English Dictionary
moleskin (ˈməʊlˌskɪn)
1.  the dark grey dense velvety pelt of a mole, used as a fur
2.  a hard-wearing cotton fabric of twill weave used for work clothes, etc
3.  (modifier) made from moleskin: a moleskin waistcoat

Collins English Dictionary - Complete & Unabridged 10th Edition
2009 © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
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Example sentences
If shoes need breaking in, place moleskin pads next to areas on the skin where friction is likely to occur.
In addition, look for moleskin footpads or other types of padding to help prevent blisters.
Blisters are another common injury so pack some moleskin.
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