noun, plural psychoses [-seez] . Psychiatry.
a mental disorder characterized by symptoms, such as delusions or hallucinations, that indicate impaired contact with reality.
any severe form of mental disorder, as schizophrenia or paranoia.

1840–50; < Late Greek psȳ́chōsis animation, principle of life. See psych-, -osis Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2014.
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World English Dictionary
psychosis (saɪˈkəʊsɪs)
n , pl -choses
Compare neurosis any form of severe mental disorder in which the individual's contact with reality becomes highly distorted
[C19: New Latin, from psycho- + -osis]

Collins English Dictionary - Complete & Unabridged 10th Edition
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Word Origin & History

1847, "mental derangement," from Gk. psykhe- "mind" (see psyche) + Mod.L. -osis "abnormal condition." Gk. psykhosis meant "animation, principle of life."
Online Etymology Dictionary, © 2010 Douglas Harper
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American Heritage
Medical Dictionary

psychosis psy·cho·sis (sī-kō'sĭs)
n. pl. psy·cho·ses (-sēz)
A severe mental disorder, with or without organic damage, characterized by derangement of personality and loss of contact with reality and causing deterioration of normal social functioning.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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American Heritage
Science Dictionary
psychosis   (sī-kō'sĭs)  Pronunciation Key 
Plural psychoses (sī-kō'sēz)
A mental state caused by psychiatric or organic illness, characterized by a loss of contact with reality and an inability to think rationally. A psychotic person often behaves inappropriately and is incapable of normal social functioning.

psychotic adjective (sī-kŏt'ĭk)
The American Heritage® Science Dictionary
Copyright © 2002. Published by Houghton Mifflin. All rights reserved.
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American Heritage
Cultural Dictionary
psychosis [(seye-koh-sis)]

A severe mental disorder, more serious than neurosis, characterized by disorganized thought processes, disorientation in time and space, hallucinations, and delusions. Paranoia, manic depression, megalomania, and schizophrenia are all psychoses. One who suffers from psychosis is psychotic.

The American Heritage® New Dictionary of Cultural Literacy, Third Edition
Copyright © 2005 by Houghton Mifflin Company.
Published by Houghton Mifflin Company. All rights reserved.
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Example sentences
Symptoms of psychosis can become gradually or suddenly evident.
It's long been known that syphilis can trigger psychosis.
Some cases, however are severe enough to cause psychosis or delusions.
Surely the unfairness in treating psychosis is knowing when to listen to
  patients and how.
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