1508, "strange, peculiar, eccentric," from Scottish, perhaps from Low Ger. (Brunswick dialect)
queer "oblique, off-center," related to Ger.
quer "oblique, perverse, odd," from O.H.G.
twerh "oblique," from PIE base
*twerk- "to turn, twist, wind" (related to
thwart). The verb "to spoil, ruin" is first recorded 1812. Sense of "homosexual" first recorded 1922; the noun in this sense is 1935, from the adj.