renin

[ree-nin]
noun Biochemistry.
a proteolytic enzyme secreted by the kidneys that is involved in the release of angiotensin.

Origin:
1890–95; ren(i)- + -in2

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Collins
World English Dictionary
renin (ˈriːnɪn)
 
n
a proteolytic enzyme secreted by the kidneys, which plays an important part in the maintenance of blood pressure
 
[C20: from reni- + -in]

Collins English Dictionary - Complete & Unabridged 10th Edition
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American Heritage
Medical Dictionary

renin re·nin (rē'nĭn, rěn'ĭn)
n.
A protein-digesting enzyme that is released by the kidneys and that catalyzes the hydrolysis of angiotensinogen to angiotensin I. Also called angiotensinogenase.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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American Heritage
Science Dictionary
renin   (rē'nĭn, rěn'ĭn)  Pronunciation Key 
A proteinase enzyme of high specificity that is released by the kidney and acts to raise blood pressure by activating angiotensin. See also angiotensin.
The American Heritage® Science Dictionary
Copyright © 2002. Published by Houghton Mifflin. All rights reserved.
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Encyclopedia Britannica
Encyclopedia

renin

enzyme secreted by the kidney (and also, possibly, by the placenta) that breaks down protein and produces a rise in blood pressure. In the blood, renin acts on a fraction of the plasma proteins and releases angiotensin I. Angiotensin II is formed by the action of converting enzyme, which splits off two amino acids from the 10-amino-acid chain of angiotensin I. The resultant octapeptide (previously called hypertensin, or angiotonin) constricts arterioles, causing a rise in both systolic and diastolic blood pressure. It is one of the most active vasoconstrictors known; on a weight basis it is about six times as potent as norepinephrine. It also increases the secretion of cortisol and aldosterone by a direct action on the adrenal cortex.

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Encyclopedia Britannica, 2008. Encyclopedia Britannica Online.
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Example sentences
Kidney secretions of renin synthesize a substance called angiotensin.
Given in tablets, it acts by inhibiting renin, an enzyme secreted primarily by the kidneys that raises blood pressure.
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