[skrey-pee, skrap-ee]
noun Veterinary Pathology.
an infectious, usually fatal brain disease of sheep, characterized by twitching of the neck and head, grinding of the teeth, and scraping of itching portions of skin against fixed objects with a subsequent loss of wool: caused by an unidentified sticky agent that clings to cell membranes.

1905–10; scrape + -ie Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2014.
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World English Dictionary
scrapie (ˈskreɪpɪ)
a disease of sheep and goats: one of a group of diseases (including BSE in cattle) that are caused by a protein prion, and result in spongiform encephalopathy
[C20: from scrape + -ie]

Collins English Dictionary - Complete & Unabridged 10th Edition
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American Heritage
Science Dictionary
scrapie   (skrā'pē, skrāp'ē)  Pronunciation Key 
A usually fatal, degenerative disease of sheep and goats, marked by chronic itching, loss of muscular coordination, and progressive deterioration of the central nervous system. While the exact cause is unknown, a prion or virus is thought to be the agent of transmission.
The American Heritage® Science Dictionary
Copyright © 2002. Published by Houghton Mifflin. All rights reserved.
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Encyclopedia Britannica


fatal neurodegenerative disease of sheep and, less often, goats. Scrapie has existed in Europe for more than 200 years and has been endemic in British sheep, particularly the Suffolk breed, since the early 18th century. It is a particular problem in the United Kingdom, Iceland, France, and Germany. It also occurs in the United States, Canada, parts of Asia, and Africa

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Encyclopedia Britannica, 2008. Encyclopedia Britannica Online.
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Example sentences
These, in turn, may have come from cross-contamination in slaughterhouses that also processed sheep with scrapie.
Scrapie is a fatal, degenerative disease affecting the central nervous system of sheep and goats.
Scrapie has had a significant impact on the sheep industry and has caused financial losses to sheep producers across the country.
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