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"junction between two nerve cells," 1899, from Greek synapsis "conjunction," from synaptein "to clasp," from syn- "together" (see syn-) + haptein "to fasten." Related to apse. Introduced by English physiologist Sir Michael Foster (1836-1907) at the suggestion of English classical scholar Arthur Woollgar Verral (1851-1912).
synapse syn·apse (sĭn'āps', sĭ-nāps')
The junction across which a nerve impulse passes from an axon terminal to a neuron, a muscle cell, or a gland cell.
The small junction across which a nerve impulse passes from one nerve cell to another nerve cell, a muscle cell, or a gland cell. The synapse consists of the synaptic terminal, or presynaptic ending, of a sending neuron, a postsynaptic ending of the receiving cell that contains receptor sites, and the space between them (the synaptic cleft). The synaptic terminal contains neurotransmitters and cell organelles including mitochondria. An electrical impulse in the sending neuron triggers the migration of vesicles containing neurotransmitters toward the membrane of the synaptic terminal. The vesicle membrane fuses with the presynaptic membrane, and the neurotransmitters are released into the synaptic cleft and bind to receptors of the connecting cell where they excite or inhibit electrical impulses. See also neurotransmitter.