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tachyphylaxis

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Tachyphylaxis
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tach⋅y⋅phy⋅lax⋅is

  [tak-uh-fi-lak-sis]
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–noun
1. Medicine/Medical. immediate, temporary immunization against the effects of injection of a toxic extract owing to previous small injections of the same extract.
2. a decreased response to a medicine given over a period of time so that larger doses are required to produce the same response.
Also, tach⋅y⋅phy⋅lax⋅i⋅a  [tak-uh-fi-lak-see-uh] .

Origin:
tachy- + Gk phýlaxis a guarding, equiv. to phylak- (s. of phylássein to guard) + -sis -sis

Related forms:
tach⋅y⋅phy⋅lac⋅tic  [tak-uh-fi-lak-tik] , adjective
Dictionary.com Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2009.
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Tachyphylaxis
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tach·y·phy·lax·is   (tāk'ə-fĭ-lāk'sĭs)   
n.   pl. tach·y·phy·lax·es (-fĭ-lāk'sēz)

  1. Rapid desensitization to a toxic substance produced by inoculation with a series of small doses.

  2. A rapidly decreasing response to a drug following administration of the initial doses.

The American Heritage® Dictionary of the English Language, Fourth Edition
Copyright © 2009 by Houghton Mifflin Company.
Published by Houghton Mifflin Company. All rights reserved.
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Medical Dictionary

Main Entry: tachy·phy·lax·is
Pronunciation: "tak-i-fi-'lak-s&s
Function: noun
Inflected Form: plural tachy·phy·lax·es /-"sEz/
: diminished response to later increments in a sequence of applications of a physiologically active substance (as thediminished pressor response that follows repeated injections of renin)
Merriam-Webster's Medical Dictionary, © 2002 Merriam-Webster, Inc.
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Medical Dictionary

tachyphylaxis tach·y·phy·lax·is (tāk'ə-fĭ-lāk'sĭs)
n.

  1. Rapid desensitization to a pharmacologically or physiologically active substance produced by inoculation with a series of small doses.

  2. A rapidly decreasing response to a drug following its initial administration.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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