"You canker blossom!" 3 Shakespearean Insults
Old English twinclian, frequentative of twincan "to wink, blink;" related to Middle High German zwinken, German zwinkern, and probably somehow imitative. The noun is recorded from 1540s. Related: Twinkled; twinkling. Phrase in the twinkling of an eye is attested from c.1300.