1. harass, vex, irritate; molest, disturb. Bother, annoy, plague, tease imply persistent interference with one's comfort or peace of mind. Bother suggests causing trouble or weariness or repeatedly interrupting in the midst of pressing duties. To annoy is to vex or irritate by bothering. Plague is a strong word, connoting unremitting annoyance and harassment. To tease is to pester, as by long-continued whining and begging.