1568, in ref. to diseases, from L. malignans, prp. of malignere (see malign (adj.)). Earlier in the church malignant "followers of the antichrist," from L. ecclesiam malignantum in early Church writing, applied by Protestant writers to the Church in Rome (1542).
Tending to have a destructive clinical course, as a malignant illness.
Relating to cancer cells that are invasive and tend to metastasize. Malignant tumor cells are histologically more primitive than normal tissue. Compare benign.
A descriptive term for things or conditions that threaten life or well-being. Malignant is the opposite of benign.
Note: The term malignant is used in describing cancerous tumors (seecancer) because such growths are a threat to the health of the individual.
Note: The term is often used in a general way to denote something that is both destructive and fast growing: “The malignant growth of the suburbs is destroying the landscape.”
Ma*lign"\, a. [L. malignus, for maligenus, i. e., of a bad kind or nature; malus bad + the root of genus birth, race, kind: cf. F. malin, masc., maligne, fem. See Malice, Gender, and cf. Benign, Malignant.]1. Having an evil disposition toward others; harboring violent enmity; malevolent; malicious; spiteful; -- opposed to benign. Witchcraft may be by operation of malign spirits. --Bacon. 2. Unfavorable; unpropitious; pernicious; tending to injure; as, a malign aspect of planets. 3. Malignant; as, a malign ulcer. [R.] --Bacon.
Ma*lig"nance\, Malignancy \Ma*lig"nan*cy\, n. [See Malignant.]1. The state or quality of being malignant; extreme malevolence; bitter enmity; malice; as, malignancy of heart. 2. Unfavorableness; evil nature. The malignancy of my fate might perhaps distemner yours. --Shak. 3. (Med.) Virulence; tendency to a fatal issue; as, the malignancy of an ulcer or of a fever. 4. The state of being a malignant. Syn: Malice; malevolence; malignity. See Malice.